Thank you to André Beer for providing this image (https://pixabay.com/users/geoworld-3911596/).
Guinea Pig
The following database tables have been arranged in three categories: Measurands, Clinical Applications and Laboratory Applications.
Measurands:
Lists all measurands that have been assessed for that species.
› Biochemistry (1 table)
Clinical Applications:
Focuses on clinically related aspects of biological variation (reference change values).
Laboratory Applications:
Focuses on laboratory related aspects of biological variation (quality standards).
Reference number relates to the citation list.
Legend:
CVI - intraindividual variation.
CVG- between individual variation.
CVA - analyser variation (reported in the study, shown in red if > 0.5 x CVI). This can be determined by replicate analyses or from quality control studies (QCM)
II - Index of Individuality. A high level indicates subject-based reference intervals (RCV) are more appropriate, a low level indicates population-based reference intervals are appropriate, intermediate levels indicate both reference change values and reference intervals should be assessed.
RCV - reference change value calculated to 95% and 99%.
These terms are explained on the ‘About BV’ page.
Biochemistry
| Measurand | Sample Type | Reference | Health Status | Breed(s) | Subjects (n) Samples Frequency | CVI (%) (95% CI) | CVG (%) (95% CI) | CVA (%) Source | II Category | RCV (95%) RCV (99%) | Comments |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Albumin | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 3.4 | 3.0 | 0.9 | 1.2 | 9.7 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (2.9-4.2) | (2.2-3.6) | Cardiac blood duplication | Intermediate | 12.4 | |||||
| weekly | |||||||||||
| Alanine Aminotransferase (ALT) | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 16.6 | 20.4 | 1.6 | 0.8 | 46.2 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (14.1-20.3) | (14.6-24.9) | Cardiac blood duplication | Intermediate | 60.8 | |||||
| weekly | |||||||||||
| Alkaline Phosphatase (ALP) | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 22.3 | 32.7 | 0.4 | 0.7 | 61.8 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (18.9-27.4) | (23.0-40.6) | Cardiac blood duplication | Low | 81.4 | |||||
| weekly | |||||||||||
| Aspartate aminotransferase (AST) | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 19.4 | 19.2 | 0.7 | 1.0 | 53.8 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (18.9-27.4) | (13.7-23.6) | Cardiac blood duplication | Intermediate | 70.8 | |||||
| weekly | |||||||||||
| Calcium | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 3.9 | 2.9 | 0.5 | 1.3 | 10.9 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (3.3-4.7) | (2.1-3.6) | Cardiac blood duplication | Intermediate | 14.3 | |||||
| weekly | |||||||||||
| Cholesterol | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 18.1 | 16.2 | 0.6 | 1.1 | 50.2 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (15.3-22.1) | (11.6-19.8) | Cardiac blood duplication | Intermediate | 66.1 | |||||
| weekly | |||||||||||
| Chloride | Serum | 71 | healthy | Cavia porcellus | 6-12/16 | 3.1 | 4.4 | 1.2 | 0.8 | 9.2 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (2.6-3.8) | (3.1-5.5) | Cardiac blood duplication | Intermediate | 12.1 | |||||
| weekly | |||||||||||
| Creatine Kinase (CK) | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 37.6 | 56.8 | 0.7 | 0.7 | 104.2 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (31.3-47.2) | (37.6-74.6) | Cardiac blood duplication | Low | 137.2 | |||||
| weekly | |||||||||||
| γ glutamyl transferase (GGT) | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 22.1 | 25.7 | 3.2 | 0.9 | 61.9 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (18.7-27.1) | (18.3-31.6) | Cardiac blood duplication | Intermediate | 81.5 | |||||
| weekly | |||||||||||
| Glucose | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 19.1 | 41.8 | 0.3 | 0.5 | 52.9 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (16.1-23.3) | (28.9-52.7) | Cardiac blood duplication | Intermediate | 69.7 | |||||
| weekly | |||||||||||
| Iron | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 7.1 | 6.2 | 0.7 | 1.1 | 26.1 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (6.0-8.6) | (4.5-7.5) | Cardiac blood duplication | Intermediate | 34.4 | |||||
| weekly | |||||||||||
| Magnesium | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 9.9 | 6.9 | 0.9 | 1.4 | 33.4 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (8.4-12.1) | (5.0-8.4) | Cardiac blood duplication | Intermediate | 44.0 | |||||
| weekly | |||||||||||
| Phosphate | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 10.5 | 9.5 | 0.6 | 1.1 | 39.2 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (8.9-12.7) | (6.9-11.5) | Cardiac blood duplication | Intermediate | 51.7 | |||||
| weekly | |||||||||||
| Sodium | Serum | 71 | healthy | Cavia porcellus | 6-12/16 | 1.8 | 3.0 | 1.1 | 0.7 | 5.8 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (1.6-2.3) | (2.1-3.7) | Cardiac blood duplication | Low | 7.7 | |||||
| weekly | |||||||||||
| Total protein | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 3.5 | 3.3 | 0.5 | 1.1 | 9.8 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (3.0-4.2) | (2.4-4.0) | Cardiac blood duplication | Intermediate | 12.9 | |||||
| weekly | |||||||||||
| Triglycerides | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 23.9 | 30.9 | 0.5 | 0.8 | 66.3 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (20.2-29.3) | (21.9-38.3) | Cardiac blood duplication | Intermediate | 87.2 | |||||
| weekly | |||||||||||
| Urea | Serum | 71 | healthy | Cavia porcellus | 8-12/16 | 15.5 | 13.5 | 1.3 | 1.1 | 57.0 | Cobas Integra 400 Plus. Sample numbers varied weekly due to volume collection size. Mixed or fixed effects models using REML. Frozen serum stability not assessed for guinea pigs. |
| Hartley tri-colour | 6 | (13.0-18.7) | (9.7-16.4) | Cardiac blood duplication | Intermediate | 75.0 | |||||
| weekly |
